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Why are bodies made for hemp CBD? How the Endocannabinoid system play a role with hemp CBD.

Why are bodies made for hemp CBD?

Receptors and their importance

If a substance is going to affect you then your body will have something called a receptor for that substance. Since a person is able to feel the effects of CBD products, this means that they have receptors for the substance – the body has been ‘made’ to react to it. These receptors occur naturally in the human body because, believe it or not, the human body actually creates cannabinoids itself! Many plants do too – carrots, ginseng, broccoli and Echinacea, for example.

The ECS (Endocannabinoid System)

The Endocannabinoid System in the human body was discovered after cannabinoids were discovered in cannabis plants, which is where it takes its name from. The ECS is composed of receptors, things that bind to them (ligands) and enzymes that modify the ligands. The receptors are named CB1 and CBD2 and the ligands are called endocannabinoids.

Receptors and Ligands – their roles

Both CB1 and CB2 receptors are located throughout the human body as well as most other organisms (but not insects). Even the most basic of organisms like hydra have an ECS. For people, you find CB1 receptors in the peripheral and central nervous system and CB2 in the cells of the immune system.

CB1                                                                                                                   

This receptor is located in the sections of our brain that are used for pain, movement, mood and memory. THC has a direct effect here but CBD can affect these areas indirectly. Reassuringly for many, CB1 receptors aren’t really found in the brain stem so a person’s basic functions such as heart rate and breathing won’t be affected by either CBD or THC.

CB2

These receptors are located on immune system cells and microglial cells. As the brain is a site that is immune-privileges, typical cells of the immune systems can’t move across the blood-brain barrier and can’t get into the brain. It is the microglial cells that work to clean up any debris leftover when neurons have completed apoptosis (cell death that is programmed). They also help to prune synapses in the developing brain.

All of this means that hemp CBD can have an effect on your body through two different pathways. It either enters through the immune system or the nervous system. It might even have an effect on other systems or organs but this isn’t yet understood.

Final thoughts

The ECS’s role is very complex. As hemp CBD can interact either indirectly or directly with the endocannabinoid system in humans, hemp CBD does exert an effect on us. The understanding of how this affects us is still being investigated. What seems to be understood though is that it doesn’t matter how we consume the CBD for its effectiveness to be felt, whether it’s broad spectrum CBD, water soluble CBD or CBD soft gels, the effects and the hemp plant benefits are the same.

Many people choose to use CBD for sleep or choose to take CBD for insomnia. The side effects of CBD are minimal but CBD health benefits are plentiful. There is a huge range of CBD supplements available and you can even buy CBD online.

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